The weekend edition of the Wall Street Journal profiled John Paulson, whose firm made $15 billion by systematically betting against the value of American homes. Paulson himself took home $4 billion.

How’d he do it? Research.

Grasping for new ideas, [Paulson researcher Paolo] Pellegrini added a “trend line” that clearly illustrated how much prices had surged lately. He then performed a “regression analysis” to smooth the ups and downs.

The answer was in front of him: Housing prices had climbed a puny 1.4% annually between 1975 and 2000, after inflation. But they had soared over 7% in the following five years, until 2005. The upshot: U.S. home prices would have to drop by almost 40% to return to their historic trend line. Not only had prices climbed like never before, but Mr. Pellegrini’s figures showed that each time housing had dropped in the past, it fell through the trend line, suggesting that an eventual drop likely would be brutal.

“This is unbelievable!” Mr. Paulson said the next morning. The chart was Mr. Paulson’s Rosetta Stone enabling him to make sens